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Diseases of Aging


The name of your medicine is MADOPAR. It contains two active ingredients called levodopa and benserazide. MADOPAR belongs to a group of medicines called antiparkinsonian agents.
Dosage Packing Price Pay now
250 mg 100 tab USD 86.00
250 mg 200 tab USD 164.00

Medications and Prescriptions

Product Brand Name: Madopar ®

1. What MADOPAR is used for: 
The name of your medicine is MADOPAR. It contains two active ingredients called levodopa and benserazide. MADOPAR belongs to a group of medicines called antiparkinsonian agents.
Antiparkinsonian agents are used to treat Parkinson's disease and work on the central nervous system. The symptoms of Parkinson's disease are caused by a deficiency of a natural substance in the nervous system. MADOPAR helps to replace this substance. By improving muscle control, MADOPAR allows more normal movements of the body.
Your doctor, however, may have prescribed MADOPAR for another purpose. Ask your doctor if you have any questions why MADOPAR has been prescribed for you.

2. Before you take MADOPAR:
Do not take MADOPAR if:
• you have had an allergic reaction to any of the ingredients listed in the Ingredients section of this leaflet
• you have taken the non-selective monoamine oxidase (MAO) inhibitors tranylcypromine (Parnate®) or phenelzine (Nardil®) within the last 2 weeks
• you have taken a combination of a selective MAO-A inhibitor such as moclobemide (Aurorix®) with a selective MAO-B inhibitor such as selegiline (Eldepryl®, Selgene®, Apo-Selegiline®)
• you have untreated heart, liver, kidney or endocrine (hormonal) disease
• you have narrow angle glaucoma (high pressure in the eye)
• you are being treated for severe mental problems
• you are under the age of 25 years old
• you are pregnant or could become pregnant.

You must tell your doctor if:
1. you are allergic to any other medicines, foods, dyes or preservatives
2. you have any other health problems including:
• diabetes
• glaucoma
• depression or other psychological disorder.
3. you are pregnant or intend to become pregnant
you should not take MADOPAR if you are pregnant or intend to become pregnant.
4. you are breastfeeding or wish to breastfeed.
you should not take MADOPAR if you are breastfeeding or intend to breastfeed.

Taking certain foods:
MADOPAR may not work as well as usual when taken with a protein rich meal.
Other medicines may interfere with MADOPAR. These medicines include:
• those containing iron (Fergon®, Ferrogradumet®, Ferrograd C®, Ferro-Grad Folic® )
• metoclopramide (Maxolon®, Metamide®, Paramax®)
• sympathomimetics eg. medicines containing ephedrine or pseudoephedrine (such as cough and cold medicines), adrenaline, isoprenaline, amphetamine
• blood pressure lowering medications containing reserpine
• some medications used to treat mental disorders
• general anaesthetics (medicines that put you to sleep before an operation). If you know you are going to have an operation, talk to your doctor beforehand.
• other antiparkinsonian agents
• opioids such as morphine, pethidine, methadone and codeine (may be present in some cough and cold or pain relieving medicines)
• antacids (medicines for heartburn, indigestion) should not be taken at the same time as MADOPAR HBS, as they interfere with the controlled release characteristics of MADOPAR HBS. Antacids can be taken at other times of the day.
Your doctor or pharmacist has a complete list of medicines to avoid while taking MADOPAR.
If you have not told your doctor about any of the above, tell them before you start taking MADOPAR. Use MADOPAR exactly as your doctor has prescribed.

How much to take: Your doctor will tell you how many MADOPAR tablets or capsules to take each day.
The dose depends on your individual symptoms and your response. The dose of MADOPAR has to be carefully adjusted for each person as your Parkinson's symptoms will not be controlled if you take too little MADOPAR. If you take too much MADOPAR, you may experience unwanted effects. It may be several weeks before the best dose for you is reached. Remember this is just a guide. This guide can be used for MADOPAR capsules or tablets. Treatment with MADOPAR is usually started with low doses eg. one MADOPAR 62.5 three or four times a day. This may be increased over the next 4 to 6 weeks until you have reached your best dose. Usually, this dose will be MADOPAR 125 three to six times a day. Your doctor may prescribe other MADOPAR tablets or capsules to be taken as well as or instead of MADOPAR 125.
MADOPAR HBS is different from other MADOPAR products. It takes longer to start working but its effects last longer. If you change from normal MADOPAR to MADOPAR HBS, you start on the same number of capsules or tablets, but this is gradually increased by your doctor.
Some people who change to MADOPAR HBS capsules might feel a little worse at first.
When you take MADOPAR HBS, your doctor may tell you to take a MADOPAR capsule or dispersible tablet in the morning as well to help maintain better control of your symptoms.
How to take it
Capsules should be swallowed whole with a glass of water or non-alcoholic drink.
MADOPAR tablets can be broken across the score line. Any tablets which do not break cleanly along the line should not be taken.
When to take it
If possible, MADOPAR should be taken at least 30 minutes before a meal or one hour after a meal.
How long to take MADOPAR
When you start MADOPAR you will need to take it long term. You may need at least 6 months before deciding if MADOPAR is working for you. Continue taking it until your doctor tells you to stop.
If you forget to take MADOPAR
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember and then go back to taking it as you would normally. Do not double a dose to make up for one you have missed.
Things you must not do
Do not stop taking MADOPAR or lower the dose without first checking with your doctor. Do not let yourself run out of medicine over the weekend or on holidays.
Do not give MADOPAR to anyone else even if their symptoms seem similar to yours.
Do not use MADOPAR to treat other complaints unless your doctor says to.
Things to be careful of
Be careful driving or operating machinery until you know how MADOPAR affects you.

3. Side Effects: 
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking MADOPAR.
MADOPAR helps most people with Parkinson's Disease but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
If side effects do occur, they may be:
• abnormal involuntary jerking movements of the body. These are usually caused if your dose is too high and will lessen or disappear when your dose is reduced.
• mental changes including agitation, anxiety, insomnia, hallucinations and delusions
• depression
• dizziness on standing up
• your urine may be a red colour.
Other common side effects especially if you have just started MADOPAR may be:
• nausea and vomiting, loss of appetite, diarrhoea, loss of taste.
Tell your doctor if you notice any of the following and they worry you:
• palpitations, diarrhoea, confusion, tiredness, skin rash or itching.
This is not a complete list of all possible side effects. Others may occur in some people and there may be some side effects not yet known.
Tell your doctor if you notice anything else that is making you feel unwell, even if it is not on this list.
Ask your doctor or pharmacist if you don't understand anything in this list.
Do not be alarmed by this list of possible side effects. You may not experience any of them.

4. Product Description: What MADOPAR looks like
There are 5 MADOPAR products to meet individual needs.
Active ingredients:
MADOPAR 125 capsules and MADOPAR HBS capsules contain levodopa 100mg and benserazide 25mg.
MADOPAR 250 capsules contain levodopa 200mg and benserazide 50mg.
Inactive ingredients:
MADOPAR Dispersible tablets contain: citric acid, maize starch, microcrystalline cellulose, magnesium stearate.
MADOPAR 62.5, 125 and 250 capsules all contain: microcrystalline cellulose, talc, povidone, magnesium stearate, indigo carmine (132), titanium dioxide (171), iron oxide (red, yellow or black - 172), gelatin. MADOPAR 62.5 also contains mannitol.
MADOPAR HBS capsules contain: mannitol, talc, povidone, magnesium stearate, calcium hydrogen phosphate, hypromellose, hydrogenated vegetable oil, indigo carmine (132), iron oxide yellow (172), titanium dioxide (171), gelatin.
MADOPAR 125 are blue/pink coloured capsules.
MADOPAR 250 are blue/brown coloured capsules.

Caution! Before starting to take this medicine, it is vital that you should consult your doctor! Do not use it on your own initiative, without medical advice.

Madopar Review:

Madopar medicine is made up of benserazide and madopar levodopa and is used basically for treatment of Parkinson’s disease. This medicine acts as a substitute for the required content in the nervous system which is lessen down due to the disease hence improving movement activities and muscle control in body. But, people under 25 years of age, pregnant women, persons who are highly reactive to allergies, the one who has heart, kidney, eye or any endocrine disease or someone who as taken MAO very recently should firmly avoid taking this medicine.

Antacids, anesthetics, opioids, blood pressure and mental disorder lowering drugs, metoclopramide and some other such medicines have a tendency to make this madopar tablets inactive toward body. Madopar Side Effects are like, red urine, dizziness, palpitations, looseness, confusion, skin rash or itching, tiredness, hallucination, agitation, nausea, vomiting and many more. But they are negligible if properly treated.

Madopar dosage is of 125 mg HBS and 250 mg. Carbidopa is also combiningly given with benseazide for the treatment. There are no such side effects of madopar but if in case you find any then you must consult you doctor without wasting any time. If you are suffering from glaucoma, diabetes, any psychological disorder, such as depression etc then also you should tell you doctor before taking these drugs. You want to be pregnant or you are pregnant in both the cases physician’s advice is must, because there are possibilities that this drug will have bad effects on your health when they are combined with other medicines that you take during pregnancy time.

How much dosage you should take of madopar is to be asked by the doctor. You should not take medicines without doctor’s advice. Until and unless it is prescribed by the doctor one should not take it.